Enantioselective Synthesis of Praziquantel | The Synaptic Leap

Enantioselective Synthesis of Praziquantel | The Synaptic Leap:

Dr. Matt Todd (the leader for the Schisto community at TSL) is proposing a Enantioselective Synthesis of Praziquantel project. Please have a look!

The aim of the project is to design and execute a catalytic, asymmetric synthesis of the active enantiomer of PZQ. The synthesis must be highly efficient and low cost. It is not enough that the synthesis works because the route needs to be scaled up for multi-ton production. The object of this open source chemistry project is therefore to share synthetic strategies and results towards this target.

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